DUSP14 purified MaxPab rabbit polyclonal antibody (D01P)
产品名称： DUSP14 purified MaxPab rabbit polyclonal antibody (D01P)
英文名称： DUSP14 purified MaxPab rabbit polyclonal antibody (D01P)
产品编号： H00011072-D01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human DUSP14 protein.
- Immunogen:
- DUSP14 (NP_008957.1, 1 a.a. ~ 198 a.a) full-length human protein.
- Sequence:
- MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGIVPDVYEKESRHLMPYWGI
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of DUSP14 expression in transfected 293T cell line (H00011072-T02) by DUSP14 MaxPab polyclonal antibody.
Lane 1: DUSP14 transfected lysate(22.30 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 11072
- GeneBank Accession#:
- NM_007026.1
- Protein Accession#:
- NP_008957.1
- Gene Name:
- DUSP14
- Gene Alias:
- MKP-L,MKP6
- Gene Description:
- dual specificity phosphatase 14
- Omim ID:
- 606618
- Gene Ontology:
- Hyperlink
- Gene Summary:
- In addition to antigen recognition by the T-cell receptor, T-cell activation requires a second signal from a costimulatory receptor, such as CD28 (MIM 186760), which interacts with B7-1 (CD80; MIM 112203) and B7-2 (CD86; MIM 601020) ligands on antigen-presenting cells. CD28 costimulation induces transcription of interleukin-2 (IL2; MIM 147680) and stabilizes newly synthesized IL2 through the activation of mitogen-activated protein kinases (MAPKs), such as ERK (e.g., MAP2K4; MIM 601335) and JNK (see MIM 601158), and the subsequent creation of AP1 transcription factor (see MIM 165160). DUSP14 is a negative regulator of CD28 signaling.[supplied by OMIM
- Other Designations:
- MKP-1 like protein tyrosine phosphatase,OTTHUMP00000164064,OTTHUMP00000164065
- Gene Pathway