RET polyclonal antibody
产品名称： RET polyclonal antibody
英文名称： RET polyclonal antibody
产品编号： PAB3380
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of RET.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human RET.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- siRNA nanoformulation against the ret/PTC1 junction oncogene is efficient in an in vivo model of papillary thyroid carcinoma.
de Martimprey H, Bertrand JR, Fusco A, Santoro M, Couvreur P, Vauthier C, Malvy C.Nucleic Acids Res. 2008 Jan;36(1):e2. Epub 2007 Dec 13.
- Entrez GeneID:
- 5979
- Protein Accession#:
- NP_066124;P07949
- Gene Name:
- RET
- Gene Alias:
- CDHF12,HSCR1,MEN2A,MEN2B,MTC1,PTC,RET-ELE1,RET51
- Gene Description:
- ret proto-oncogene
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq
- Other Designations:
- RET transforming sequence,cadherin family member 12,hydroxyaryl-protein kinase,oncogene RET,receptor tyrosine kinase,ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Adenocarcinoma, Follicular
- Adenocarcinoma, Papillary
- Adenoma
- Adrenal Gland Neoplasms
- Alzheimer Disease
- Atherosclerosis
- Atherosclerosis
- Carcinoma
- Carcinoma, Medullary
- Carcinoma, Papillary
- Carcinoma, Papillary, Follicular
- Cleft Lip
- Cleft Palate
- Digestive System Abnormalities
- Disease Progression
- Down Syndrome
- Endocrine Gland Neoplasms
- Esophageal Neoplasms