Uniprot ID:P15696
Species Reactivity:Bovine
Antibody type:Polyclonal Antibody
Aliases:Antiluteolysin,Trophoblast antiluteolytic protein,Trophoblast protein 1,Trophoblastin,IFNT1Raised in:Rabbit
Background\Function :Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties. In contrast with other IFNs, IFN-tau is not virally inducible.
Stroage Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purity:Caprylic Acid Ammonium Sulfate Precipitation purified
武汉华美生物工程有限公司专营基因、蛋白、抗体、ELISA试剂盒、诊断试剂原料、药物残留、食品安全小分子及其他小分子等高质量生物产品，我们的产品涉及血管生成、细胞凋亡/自噬、合成/代谢、血液凝固、细胞粘附、细胞周期、补体、发育蛋白、DNA损伤/DNA修复、细胞因子、药物残留与食品安全、受精作用、生长因子、神经生物学、氧化应激、信息受体、转录/转录调控、运输、泛素、信号传导通路、自身免疫等多个研究领域，包括涵盖37个种属的多达万种的ELISA试剂盒。详细信息请登录：www.cusabio.cn/