TRIM33 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
TRIM33 抗体

TRIM33 抗体

商家询价

产品名称： TRIM33 抗体

英文名称： TRIM33 Antibody

产品编号： XY55374-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 TRIM33 抗体Applications

In-house applications ELISA, WB     Application not tested? Please see our Guarantee.
Species specificity Human; other species not tested.
Images
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  • 55374-1-AP;COLO 320 cellCOLO 320 cells were subjected to SDS PAGE followed by western blot with 55374-1-AP(TRIM33 antibody) at dilution of 1:500
Positive WB detected in COLO 320 cells, MCF7 cells, PC-3 cells
Recommended dilution WB : 1:200-1:2000
 TRIM33 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information TRIM33 抗体
Immunogen Peptide Full name Tripartite motif-containing 33
Calculated molecular
weight		 122 kDa Observed molecular 
weight		 140-150 kDa
GenBank accession 
number		 NM_015906 Gene ID (NCBI) 51592
Gene symbol TRIM33 Synonyms Ectodermin homolog, FLJ32925, KIAA1113, Protein Rfg7, PTC7, RET fused gene 7 protein, RFG7, TF1G, TIF1 gamma, TIF1G, TIF1GAMMA, TIFGAMMA, TRIM33, tripartite motif containing 33
Background

TRIM33, also named as KIAA1113, RFG7 and TIF1G, belongs to the TRIM/RBCC family. It acts as an E3 ubiquitin-protein ligase. TRIM33 promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. It may act as a transcriptional repressor. It inhibits the transcriptional response to TGF-beta/BMP signaling cascade. TRIM33 plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3, TRIM33 stimulates erythroid differentiation of hematopoietic stem/progenitor. Defects in TRIM33 are a cause of thyroid papillary carcinoma (TPC). This antibody is specific to TRIM33. TRIM33 抗体

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