FITC标记的磷脂酰肌醇激酶3催化亚单位3抗体-抗体-抗体-生物在线
上海沪震实业有限公司
FITC标记的磷脂酰肌醇激酶3催化亚单位3抗体

FITC标记的磷脂酰肌醇激酶3催化亚单位3抗体

商家询价

产品名称: FITC标记的磷脂酰肌醇激酶3催化亚单位3抗体

英文名称: Anti-PI 3 Kinase Class 3/FITC

产品编号: HZ-4159R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: Flow-Cyt=1:50-200 IF=1:50-200

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 Rabbit Anti-PI 3 Kinase Class 3/FITC Conjugated antibody

FITC标记的磷脂酰肌醇激酶3催化亚单位3抗体

 

英文名称 Anti-PI 3 Kinase Class 3/FITC
中文名称 FITC标记的磷脂酰肌醇激酶3催化亚单位3抗体
别    名 PI 3 Kinase Class 3; Phosphatidylinositol 3 kinase catalytic subunit type 3; Phosphatidylinositol 3 kinase class 3; Phosphatidylinositol 3 kinase p100 subunit; Phosphoinositide 3 kinase class 3; PI3 kinase type 3; PI3K type 3; PIK3C3; PtdIns 3 kinase type 3; Vps 34; Vps34; hVps34; MGC61518; PIK3C3; PI3 Kinase p100; PK3C3_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 免疫学  信号转导  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, 
产品应用 Flow-Cyt=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 98kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PIK3C3/PI3 kinase type 3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
PI 3 Kinase Class 3 is a member of the PI3/PI4-kinase family. It is the catalytic subunit of the PI3K complex. It is involved in the transport of lysosomal enzyme precursors to lysosomes. It is ubiquitously expressed, with a highest expression in skeletal muscle.

Function:
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.

Subunit:
Heterodimer. This subunit, part of a complex composed of regulatory and catalytic subunits, associates with regulatory subunit PIK3R4. Forms a complex with BECN1, PIK3R4 and either UVRAG and KIAA0226/Rubicon, or with ATG14. In this complex, presence of UVRAG and ATG14 are mutually exclusive. Part of a complex composed of PIK3R4 and PIK3CB (By similarity). Interacts with RAB7A in the presence of PIK3R4.

Subcellular Location:
Midbody. Late endosome.

Tissue Specificity:
Ubiquitously expressed, with a highest expression in skeletal muscle.

Similarity:
Belongs to the PI3/PI4-kinase family. 
Contains 1 C2 PI3K-type domain. 
Contains 1 PI3K/PI4K domain. 
Contains 1 PIK helical domain. 

Database links:

Entrez Gene: 5289 Human

Entrez Gene: 225326 Mouse

Entrez Gene: 65052 Rat

Omim: 602609 Human

SwissProt: Q8NEB9 Human

SwissProt: Q6PF93 Mouse

SwissProt: O88763 Rat

Unigene: 464971 Human

Unigene: 194127 Mouse

Unigene: 30010 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   
   

PI 3激酶类3是PI3/PI4激酶家族的成员。它是PI3K络合物的催化亚基。它涉及溶酶体酶前体向溶酶体的运输。它在骨骼肌中普遍表达,具有最高的表达。