FITC标记的高尔基体蛋白A亚基4抗体
产品名称： FITC标记的高尔基体蛋白A亚基4抗体
英文名称： Anti-Golgin subfamily A member 4/FITC
产品编号： HZ-13487R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Golgin subfamily A member 4/FITC Conjugated antibody
FITC标记的高尔基体蛋白A亚基4抗体
| 英文名称 | Anti-Golgin subfamily A member 4/FITC |
| 中文名称 | FITC标记的高尔基体蛋白A亚基4抗体 |
| 别 名 | 256 kDa golgin; 72.1 protein; GCP2; GOGA4_HUMAN; GOLG; GOLGA4; golgi autoantigen, golgin subfamily a, 4; Golgin subfamily A member 4; golgin-240; Golgin-245; MU-RMS-40.18; OTTHUMP00000161363; OTTHUMP00000208897; OTTHUMP00000209805; p230; Protein 72.1; Trans-Golgi p230; Golgin 245. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 转运蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 261kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Golgin subfamily A member 4/Golgin 245 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈. |
| 产品介绍 | background: Golgin 245 is also known as p230, GCP2, GOLG or golgi autoantigen and is a 2,230 amino acid protein that is expressed as three isoforms. Golgin 245 is localized to the cytoplasm in cells and is a member of the golgin family, all of which are peripheral membrane proteins associated with the Golgi complex. Golgin 245 has a carboxyl-terminal GRIP domain, which attaches to the trans-Golgi network (TGN) and TGN-derived vesicles. It is thought that the interaction that takes place between golgin 245 and MACF1, which cross-links microtubules to the Actin cytoskeleton, allows proteins to be transported from the TGN to the cell periphery. Antibodies against golgin 245 are associated with two chronic disorders known as Sj鰃ren's syndrome and Hepatitis B. Function: May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1. Subunit: Homodimer. Interacts with GTP bound ARL1. Interacts with MACF1. Subcellular Location: Cytoplasm. Golgi apparatus membrane. Golgi apparatus. Similarity: Contains 1 GRIP domain. Database links: Entrez Gene: 2803 Human Omim: 602509 Human SwissProt: Q13439 Human Unigene: 344151 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
Golgin 245也被称为p230、GCP2、GOLG或高尔基体自身抗原，是一种2230氨基酸的蛋白质，以三种异构体表达。Golgin 245定位于细胞中的细胞质，是golgin家族的成员，所有这些都是与高尔基复合物相关的外周膜蛋白。Golgin 245具有羧基末端握持结构域，其连接到跨高尔基网络（TGN）和TGN衍生囊泡。据认为，在高尔金245和MACF1之间发生的相互作用，使微管与肌动蛋白细胞骨架交联，允许蛋白质从TGN运输到细胞外围。抗GalGin 245抗体与两种被称为Sj-Lee综合征和乙型肝炎的慢性疾病相关。