FITC标记的22号染色体开放阅读框36抗体
产品名称： FITC标记的22号染色体开放阅读框36抗体
英文名称： Anti-C22orf36/FITC
产品编号： HZ-9986R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-C22orf36/FITC Conjugated antibody
FITC标记的22号染色体开放阅读框36抗体
| 产品编号 | bs-9986R-FITC |
| 英文名称 | Anti-C22orf36/FITC |
| 中文名称 | FITC标记的22号染色体开放阅读框36抗体 |
| 别 名 | C22orf36; Leucine-rich repeat-containing protein C22orf36; chromosome 22 open reading frame 36; LRC6X_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 35kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human C22orf36 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: C22orf36 is a 315 amino acid protein that contains two LRR (leucine-rich) repeats and exists as two alternatively spliced isoforms. C22orf36 is encoded by a gene located on human chromosome 22, which contains over 500 genes and about 49 million bases. As the second smallest human chromosome, chomosome 22 contains a wide variety of genes with numerous functions. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein, BCR-Abl, a potent cell proliferation activator found in several types of leukemia. Similarity: Belongs to the FAM211 family. Contains 2 LRR (leucine-rich) repeats. Database links: Entrez Gene: 388886 Human SwissProt: Q2VPJ9 Human Unigene: 113314 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
C22OrF36是含有两个LRR（亮氨酸富集）重复序列的315个氨基酸的蛋白质，存在两个交替剪接的异构体。C22Orf36编码的基因位于人类22号染色体上，含有500个以上的基因，约有4900万个碱基。作为第二个最小的人类染色体，ChoSCOME 22包含多种功能的基因。PelLAN McDeMID综合征，2型神经纤维瘤病和孤独症与22号染色体有关。在22号染色体上发现精神分裂症易感性位点，研究表明22q11缺失症状包括精神分裂症的高发病率。染色体9和5月22日间的易位导致了费城染色体的形成和随后产生的新型融合蛋白BCR-ABL，这是一种在多种类型的白血病中发现的强有力的细胞增殖激活剂。