Anti-A2M Polyclonal Antibody
产品名称: Anti-A2M Polyclonal Antibody
英文名称: A2MD;CPAMD5;FWP007;S863-7
产品编号: K002843P
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: null
使用范围: WB IF
北京索莱宝科技有限公司--实验室产品
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The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified.