PPP2R4 polyclonal antibody
产品名称： PPP2R4 polyclonal antibody
英文名称： PPP2R4 polyclonal antibody
产品编号： PAB14148
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of PPP2R4.
- Immunogen:
- A synthetic peptide corresponding to human PPP2R4.
- Sequence:
- C-GSLLPIHPVTSG
- Host:
- Goat
- Theoretical MW (kDa):
- 40.7, 36.8, 31.9
- Reactivity:
- Human, Rat
- Specificity:
- Approx 37 KDa band observed in lyastes of human liver tissue and HepG2 cell line (calculated MW of 36.8 KDa according to NP_066954.2).
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:32000)
Western Blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Protein phosphatase 2A negatively regulates integrin alpha(IIb)beta(3) signaling.
Gushiken FC, Patel V, Liu Y, Pradhan S, Bergeron AL, Peng Y, Vijayan KV.J Biol Chem. 2008 May 9;283(19):12862-9. Epub 2008 Mar 11.
- Applications
- Western Blot (Tissue lysate)
- PPP2R4 polyclonal antibody (Cat # PAB14148) (0.5 ug/mL) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
- Entrez GeneID:
- 5524
- Protein Accession#:
- NP_821068.1;NP_066954.2;NP_821070.1
- Gene Name:
- PPP2R4
- Gene Alias:
- MGC2184,PP2A,PR53,PTPA
- Gene Description:
- protein phosphatase 2A activator, regulatory subunit 4
- Omim ID:
- 600756
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
- Other Designations:
- OTTHUMP00000022333,PP2A phosphatase activator,PP2A, subunit B',phosphotyrosyl phosphatase activator,protein phosphatase 2A, regulatory subunit B',protein phosphatase 2A, regulatory subunit B' (PR 53)
- Related Disease