BRD8 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
BRD8 抗体

BRD8 抗体

商家询价

产品名称： BRD8 抗体

英文名称： BRD8 Antibody

产品编号： XY10476-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 BRD8 抗体

Applications
In-house applications ELISA, WB, IP, IF     Application not tested? Please see our Guarantee.
Species specificity Human; other species not tested.
Images
Prev1NextView more validation data
  • 10476-1-AP;HeLa cellsHeLa cells were subjected to SDS PAGE followed by western blot with 10476-1-AP(BRD8 antibody) at dilution of 1:500
  • 10476-1-AP;HeLa cellsIP Result of anti-BRD8 (IP:10476-1-AP, 4ug; Detection:10476-1-AP 1:300) with HeLa cells lysate 1200ug.
  • 10476-1-AP;HeLa cellsImmunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using 10476-1-AP( BRD8 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Positive WB detected in HeLa cells, human brain tissue
Positive IP detected in HeLa cells
Positive IF detected in HeLa cells
Recommended dilution WB : 1:200-1:2000
IP : 1:200-1:1000
IF : 1:50-1:500
 BRD8 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen BRD8 fusion protein ag0790 Full name Bromodomain containing 8
Calculated molecular
weight		 120 kDa Observed molecular 
weight		 120 kDa
GenBank accession 
number		 BC008039 Gene ID (NCBI) 10902
Gene symbol BRD8 Synonyms BRD8, bromodomain containing 8, p120, SMAP, SMAP2, TrCP120
Background BRD8 抗体

BRD8 is one of the bromodomain-containing proteins, which is an acetylated lysine- binding domain and thought to be involved in regulation of protein acetylation and/or HAT (histone acetyl transferase) activity [PMID: 12963728]. It is also reported to be an accessory subunit of NuA4 HAT complex (also known as TRRAP/TIP60 complex) through biochemical purification [PMID: 16049979]. In addition, it can bind to thyroid hormone receptor-ß and/or retinoid X receptor, and can act as a coactivator of the nuclear hormone receptor-mediated transcription in reporter assays [PMID: 10517671]. BRD8 抗体

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