YY1 (N-term) Peptide
产品名称： YY1 (N-term) Peptide
英文名称： YY1 (N-term) Peptide
产品编号： P1130
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of YY1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human YY1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Nuclear factor YY1 inhibits transforming growth factor beta- and bone morphogenetic protein-induced cell differentiation.
Kurisaki K, Kurisaki A, Valcourt U, Terentiev AA, Pardali K, Ten Dijke P, Heldin CH, Ericsson J, Moustakas A.Mol Cell Biol. 2003 Jul;23(13):4494-510.
- 2.
- Modulation of YY1 activity by SAP30.
Huang NE, Lin CH, Lin YS, Yu WC.Biochem Biophys Res Commun. 2003 Jun 20;306(1):267-75.
- 3.
- Yin Yang 1 is increased in human heart failure and represses the activity of the human alpha-myosin heavy chain promoter.
Sucharov CC, Mariner P, Long C, Bristow M, Leinwand L.J Biol Chem. 2003 Aug 15;278(33):31233-9. Epub 2003 May 16.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of YY1 polyclonal antibody (Cat # PAB4360) in HeLa cell lysate . YY1 (arrow) was detected using purified YY1 polyclonal antibody (Cat # PAB4360) . Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence .
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with YY1 polyclonal antibody (Cat # PAB4360) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . HC = hepatocarcinoma .
- Entrez GeneID:
- 7528
- Protein Accession#:
- P25490
- Gene Name:
- YY1
- Gene Alias:
- DELTA,INO80S,NF-E1,UCRBP,YIN-YANG-1
- Gene Description:
- YY1 transcription factor
- Omim ID:
- 600013
- Gene Ontology:
- Hyperlink
- Gene Summary:
- YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1. [provided by RefSeq
- Other Designations:
- INO80 complex subunit S,Yin and Yang 1 protein
- Related Disease