RAMP1 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
RAMP1 抗体

RAMP1 抗体

商家询价

产品名称: RAMP1 抗体

英文名称: RAMP1 Antibody

产品编号: XY10327-1-

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

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 RAMP1 抗体Applications

In-house applications ELISA, WB, IHC, FC     Application not tested? Please see our Guarantee.
Published applications IF Publications 1 citations –view here
Species specificity Human; other species not tested.
Published Species Rat
Images
Prev12NextView more validation data
  • 10327-1-AP;human heart tissuehuman heart tissue were subjected to SDS PAGE followed by western blot with 10327-1-AP(RAMP1 antibody) at dilution of 1:300
  • 10327-1-AP;human small intestine tissueImmunohistochemistry of paraffin-embedded human small intestine tissue slide using 10327-1-AP( RAMP1 Antibody) at dilution of 1:200 (under 10x lens).
  • 10327-1-AP;human small intestine tissueImmunohistochemistry of paraffin-embedded human small intestine tissue slide using 10327-1-AP( RAMP1 Antibody) at dilution of 1:200 (under 40x lens).
  • 10327-1-AP;HepG2 cells1X10^6 HepG2 cells were stained with .2ug RAMP1 antibody (10327-1-AP, red) and control antibody (blue). Fixed with 4% PFA blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1500.
Positive WB detected in Human heart tissue
Positive IHC detected in Human small intestine tissue
Positive FC detected in HepG2 cells
Recommended dilution WB : 1:200-1:2000
IHC : 1:50-1:500
 RAMP1 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information RAMP1 抗体
Immunogen RAMP1 fusion protein ag0402 Full name Receptor (G protein-coupled) activity modifying protein 1
Calculated molecular
weight
17 kDa Observed molecular 
weight
14 kDa
GenBank accession 
number
BC000548 Gene ID (NCBI) 10267
Gene symbol RAMP1 Synonyms RAMP1
Background

RAMP1 (receptor-activity-modifying protein) is a member of the RAMP family of single-transmembrane-domain proteins which consist of an N-terminal extracellular domain, a transmembrane region and a short intracellular C-terminal tail. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a G protein-coupled receptor, can function as either a calcitonin gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. RAMP1 transports the CRLR to the plasma membrane and then remains associated with it to function as a terminally glycosylated CGRP receptor, while RAMP2 and RAMP3 transfer the CRLR to the cell surface to generate receptors that are preferentially selective for adrenomedullin. (PMID: 9620797; 16188935) RAMP1 抗体

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