FITC标记的高迁移率家族蛋白3抗体
产品名称： FITC标记的高迁移率家族蛋白3抗体
英文名称： Anti-HMG4/HMGB3/FITC
产品编号： HZ-8809R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-HMG4/HMGB3/FITC Conjugated antibody
FITC标记的高迁移率家族蛋白3抗体
| 英文名称 | Anti-HMG4/HMGB3/FITC |
| 中文名称 | FITC标记的高迁移率家族蛋白3抗体 |
| 别 名 | High mobility group (nonhistone chromosomal) protein 4; High mobility group box 3; High mobility group protein 2a; High mobility group protein 4; High mobility group protein B3; High mobility group protein HMG4; HMG 4; HMG-2a; HMG-4; HMG2A; HMGB 3; HMGB3; HMGB3_HUMAN; MGC90319; Non histone chromosomal protein; Nonhistone chromosomal protein HMG4. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 转录调节因子 结合蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 23kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HMG4/HMGB3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: HMGB3 belongs to the high mobility group (HMG) protein superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription (Wilke et al., 1997 [PubMed 9370291]; Nemeth et al., 2006 [PubMed 16945912]).[supplied by OMIM, Mar 2008] Function: Binds preferentially single-stranded DNA and unwinds double stranded DNA. Subcellular Location: Nucleus. Chromosome. Tissue Specificity: Expressed predominantly in placenta. Similarity: Belongs to the HMGB family. Contains 2 HMG box DNA-binding domains. Database links: Entrez Gene: 3149 Human Entrez Gene: 613729 Cow Entrez Gene: 15354 Mouse Entrez Gene: 305373 Rat Omim: 300193 Human SwissProt: Q32L31 Cow SwissProt: O15347 Human SwissProt: O54879 Mouse Unigene: 19114 Human Unigene: 336087 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
HMGB3属于高迁移率族蛋白（HMG）超家族。与HMG1（MIM 163905）和HMG2（MIM 163906）一样，HMGB3包含DNA结合的HMG盒结构域，并被归入HMG盒亚家族。HMG盒亚家族的成员被认为在DNA复制、核小体组装和转录中发挥基本作用(Wilke等人，1997[PubMed 9370291]；Nemeth等人，2006[PubMed 16945912])。