磷酸二酯酶 I
产品名称： 磷酸二酯酶 I
英文名称： Phosphodiesterase I
产品编号： PLS003926
产品价格： 0
产品产地： usa
品牌商标： worthington
更新时间： null
使用范围： null
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Phosphodiesterase I from Crotalus adamanteus Venom 磷酸二酯酶 I
CAS:9025-82-5
Source: Crotalus adamanteus Venom
I.U.B.: 3.1.4.1
Venom exonuclease (Phosphodiesterase I) successively hydrolyzes 5-mononucleotides from 3-OH-terminated ribo- and deoxyribo-oligonucleotides. The enzyme has an optimal pH range of 9.8-10.4 and a molecular weight of 115 kDa. Phosphodiesterase is inhibited by reducing agents such as glutathione, cysteine and ascorbic acids. It is completely inhibited by 5mM EDTA while ATP, ADP and AMP are partial inhibitors. The enzyme has an absolute requirement for Mg2+.
Unit Definition: One Unit hydrolyzes one micromole of p-nitrophenyl thymidine-5-phosphate per minute at 25°C, pH 8.9.