FITC标记的线粒体裂变1蛋白抗体
产品名称: FITC标记的线粒体裂变1蛋白抗体
英文名称: Anti-FIS1/FITC
产品编号: HZ-7646R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-FIS1/FITC Conjugated antibody
FITC标记的线粒体裂变1蛋白抗体
英文名称 | Anti-FIS1/FITC |
中文名称 | FITC标记的线粒体裂变1蛋白抗体 |
别 名 | CGI 135; CGI135; FIS 1; FIS1; Fis1 homolog; FIS1, S. cerevisiae, homolog of; FIS1_HUMAN; Fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae); Fission 1 (mitochondrial outer membrane) homolog (yeast); Fission 1 (mitochondrial outer membrane) homolog; Fission 1 homolog; hFis 1 hFis1; Mitochondrial fission 1 protein; Tetratricopeptide repeat domain 11; Tetratricopeptide repeat protein 11; TPR repeat protein 11; TTC 11. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 细胞凋亡 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 17kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human FIS1 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Promotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission. Function: Promotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission. Subunit: Interacts with DNM1L/DLP1 through the TPR region. Interacts with MARCH5. Interacts with MID51. Subcellular Location: Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein. Post-translational modifications: Ubiquitinated by MARCH5. Similarity: Belongs to the FIS1 family. Contains 1 TPR repeat. Database links: Entrez Gene: 51024 Human Entrez Gene: 66437 Mouse Entrez Gene: 288584 Rat Omim: 609003 Human SwissProt: Q9Y3D6 Human SwissProt: Q9CQ92 Mouse SwissProt: P84817 Rat Unigene: 423968 Human Unigene: 25849 Mouse Unigene: 1298 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
促进the碎片of the及其抗线粒体网络聚类。能导致细胞色素C释放from the mitochondrion to the胞凋亡,最终导向。also mediates过氧化物酶体裂变。