RB1 monoclonal antibody, clone 1D1
产品名称： RB1 monoclonal antibody, clone 1D1
英文名称： RB1 monoclonal antibody, clone 1D1
产品编号： MAB2168
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant RB1.
- Immunogen:
- Recombinant protein corresponding to amino acids 571-590 of RB1.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- This antibody recognizes an epitope within aa 571-590 of RB1.
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In PBS, pH 7.4
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Retinoblastoma protein monoclonal antibodies with novel characteristics.
Wen SF, Nodelman M, Nared-Hood K, Duncan J, Geradts J, Shepard HM.J Immunol Methods. 1994 Mar 10;169(2):231-40.
- Application Image
- Western Blot
- Immunoprecipitation
- ELISA
- Entrez GeneID:
- 5925
- Gene Name:
- RB1
- Gene Alias:
- OSRC,RB,p105-Rb,pRb,pp110
- Gene Description:
- retinoblastoma 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq
- Other Designations:
- OTTHUMP00000018397,retinoblastoma suspectibility protein,retinoblastoma-associated protein
- Related Disease
- Adenocarcinoma
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma, Hepatocellular
- Carcinoma, Squamous Cell
- Chromosomal Instability
- Chromosome Aberrations
- Chromosome Deletion
- Colorectal Neoplasms
- Cystadenocarcinoma, Serous
- Disease Progression
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
- Liver Neoplasms
- Lung Neoplasms
- Lymphoma, Mantle-Cell
- Neoplasm Invasiveness