MAPKAPK5 polyclonal antibody
产品名称： MAPKAPK5 polyclonal antibody
英文名称： MAPKAPK5 polyclonal antibody
产品编号： PAB2779
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of MAPKAPK5.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to residues surrounding T182 of human MAPKAPK5.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- p62 functions as a p38 MAP kinase regulator.
Sudo T, Maruyama M, Osada H.Biochem Biophys Res Commun. 2000 Mar 16;269(2):521-5.
- 2.
- PRAK, a novel protein kinase regulated by the p38 MAP kinase.
New L, Jiang Y, Zhao M, Liu K, Zhu W, Flood LJ, Kato Y, Parry GC, Han J.EMBO J. 1998 Jun 15;17(12):3372-84.
- 3.
- MAPKAPK5, a novel mitogen-activated protein kinase (MAPK)-activated protein kinase, is a substrate of the extracellular-regulated kinase (ERK) and p38 kinase.
Ni H, Wang XS, Diener K, Yao Z.Biochem Biophys Res Commun. 1998 Feb 13;243(2):492-6.
- Entrez GeneID:
- 8550
- Protein Accession#:
- NP_003659;Q8IW41
- Gene Name:
- MAPKAPK5
- Gene Alias:
- PRAK
- Gene Description:
- mitogen-activated protein kinase-activated protein kinase 5
- Omim ID:
- 606723
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
- Other Designations:
- p38-regulated/activated protein kinase
- Interactome
- Gene Pathway