KINDLIN 2抗体
Applications
| In-house applications |
ELISA, WB, IHC, IF, IP Application not tested? Please see our Guarantee. |
| Published applications |
IF, IHC, IP, WB |
Publications |
8 citations –view here |
| Species specificity |
Human,Mouse,Rat; other species not tested. |
| Published Species |
Hamster, human, mouse, rat, zebrafish |
|
Images
Prev12Next
 A549 cells were subjected to SDS PAGE followed by western blot with 11453-1-AP(FERMT2 antibody) at dilution of 1:500 IP Result of anti-FERMT2 (IP:11453-1-AP, 3ug; Detection:11453-1-AP 1:1000) with A549 cells lysate 3300ug. Immunohistochemical of paraffin-embedded human ovary tumor using 11453-1-AP(FERMT2 antibody) at dilution of 1:50 (under 10x lens) Immunofluorescent analysis of HepG2 cells, using FERMT2 antibody 11453-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
|
| Positive WB detected in |
A549 cells, human placenta tissue |
| Positive IP detected in |
A549 cells |
| Positive IHC detected in |
Human ovary tumor tissue |
| Positive IF detected in |
HepG2 cells |
| Recommended dilution |
WB : 1:500-1:5000
IP : 1:500-1:5000
IHC : 1:20-1:200
IF : 1:10-1:100 |
KINDLIN 2抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
| Source |
Rabbit |
Purification method |
Antigen affinity purification |
| Isotype |
IgG |
Storage |
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information KINDLIN 2抗体
| Immunogen |
Kindlin 2 fusion protein ag2013 |
Full name |
Fermitin family homolog 2 (Drosophila) |
Calculated molecular
weight |
680aa,78 kDa |
Observed molecular
weight |
78 kDa |
GenBank accession
number |
BC017327 |
Gene ID (NCBI) |
10979 |
| Gene symbol |
FERMT2 |
Synonyms |
DKFZp686G11125, Fermitin family homolog 2, FERMT2, FLJ34213, FLJ44462, KIND2, Kindlin 2, mig 2, MIG2, PLEKHC1, UNC112, UNC112B |
Background
|
FERMT2, also named as KIND2, MIG2, PLEKHC1, MIG-2 and Kindlin-2, belongs to the kindlin family. There are three FERMT2 isoforms that participate in the connection between extracellular matrix (ECM) adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. FERMT2 recruits migfilin (FBLP1) protein to cell-ECM focal adhesion sites. Variable expression in human cancers and mesenchymal cancer invasion are now linked with FERMT2, which may plays important role in carcinormas development. Catalog#11453-1-AP is a rabbit polyclonal antibody against human FERMT2. KINDLIN 2抗体
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